Cascara Sagrada 3:1 Powdered Extract (4128) is a dry bark extract of Frangula purshiana on maltodextrin, standardized to the labeled 3:1 concentration named in the product. It serves supplement developers who need a defined-spec cascara powder for capsules and tablets, cold-extracted through Bio-Botanica's Bio-Chelated process.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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See our full sample process →Cascara Sagrada 3:1 Powdered Extract is a dry extract of Frangula purshiana bark on a maltodextrin carrier, supplied at the 3:1 concentration named in the product. Part 4128 gives formulators a defined-ratio cascara bark powder as a factual product spec, without tying that ratio to any marker compound or health outcome. It is a fit when your documentation calls for a labeled 3:1 extract.
Buyers increasingly ask for defined-spec botanical powders that simplify formula documentation, and cascara bark is a heritage entry in the digestive-support set. Fact.MR projects a 6.5% CAGR for cascara sagrada extract, lifting the segment to nearly US$115.6 million by 2034. A labeled 3:1 powder answers demand for consistent, spec-driven cascara inputs.
The 4128 grade fits encapsulation and tableting where a stated 3:1 concentration ratio helps standardize a formula and its label copy. Frangula purshiana bark is traditionally used to support occasional regularity and digestive comfort, so brands can position this defined-spec powder around dependable, tradition-based digestive-support products in capsule or tablet form.
Bio-Botanica has operated as a family-owned botanical manufacturer in Hauppauge, New York since 1972, producing extracts in an FDA-inspected cGMP facility. The Bio-Chelated low-heat cold-extraction process maintains the native bark profile, and every 3:1 lot passes identity, microbial, USP, and heavy-metal testing on instrumentation such as UPLC-MS/MS, LC/MS, and ICP/MS. With NSF, cGMP, and FSSC 22000 systems and Kosher, Halal, and Organic options, spec-focused formulators gain a documented partner.
It is the labeled concentration ratio at which this powdered bark extract is supplied, stated as a factual product spec. We do not tie it to a marker compound or a health benefit.
It is a powdered extract of Frangula purshiana bark, the cascara sagrada source. Only the bark is used.
The carrier is maltodextrin, supporting a dry, free-flowing 3:1 powder; the Spec Sheet/TDS has the details.
Both are maltodextrin-carried Frangula purshiana bark powders; 4128 is supplied at a labeled 3:1 concentration, while 4127SD is full-spectrum and non-standardized. Pick 4128 when your formula requires the defined 3:1 spec.
It suits two-piece capsules and tablets, as well as defined-spec dry blends.
Requested samples arrive with a Spec Sheet/TDS, a representative COA, and an SDS.
Identity, microbial, USP, and heavy-metal testing are performed in Bio-Botanica's onsite lab using instrumentation including UPLC-MS/MS, LC/MS, and ICP/MS, with third-party lab support.
Yes. Kosher, Halal, and Organic documentation is available for the 3:1 powder on request.
We do not post pricing online; each quote reflects your volume and specifications.
It is produced with the proprietary Bio-Chelated low-heat cold-extraction process to preserve the Holistically Balanced bark profile.